Radiopharmaceuticals: Introduction to Drug Evaluation and Dose Estimation

"This comprehensive overview details the process of radiopharmaceutical development, from cellular studies to animal experiments to the design and implementation of clinical trials. It examines the relative benefits of various radiopharmaceuticals and provides guidance on dose estimation and ag...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijä: Williams, Lawrence E.
Aineistotyyppi: Kirja
Kieli:englanti
Julkaistu: Boca Raton, FL CRC Press An Imprint of Taylor & Francis Group 2020
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020 |a 9780367577056 
082 |a 615.8424  |b WIL 
100 |a Williams, Lawrence E.  |9 8417 
245 |a Radiopharmaceuticals: Introduction to Drug Evaluation and Dose Estimation 
260 |a Boca Raton, FL  |b CRC Press An Imprint of Taylor & Francis Group  |c 2020 
300 |a xxii, 304 p.  
520 |a "This comprehensive overview details the process of radiopharmaceutical development, from cellular studies to animal experiments to the design and implementation of clinical trials. It examines the relative benefits of various radiopharmaceuticals and provides guidance on dose estimation and agent selection. Utilizing figures of merit for quantitative assessment, it covers standard medical internal radiation dose (MIRD), absorbed dose method for imaging agents, vivo methods for obtaining activity data, errors of activity estimation techniques, phantom-based and patient-based dose estimates and their associated uncertainties, and options available to clinical physicists. Supported by numerous examples from clinical trials, it discusses two and three dimensional estimation processes, including modern hybrid scanners such as SPECT /CT and PET/CT" 
650 |a Radiopharmaceuticals  |9 8418 
650 |a Drugs - Dosage  |9 8272 
650 |a Clinical Trials  |9 8398